We aim at providing a state-of-the-art solution to develop therapies in a rapid and economical manner. Modelis is revolutionizing the outdated target-based drug-discovery pipeline by offering an unbiased approach using multiple model organisms. Our innovative and unprejudiced approach maximizes discovery of new drugs and repurposes known molecules rare diseases.
However far from a worm or a fish we may feel and look, 80% of the genes causing human diseases are evolutionarily conserved in these animals. For example, the molecular basis of cancer or the main neuronal networks are present in these species and function like ours. Thus, these simple models are suitable for investigating a wide range of human disorders. Thanks to their small size, worms and fish are central in Modelis’ drive aiming at offering a fast and cost-friendly approach.
While the classical approach is focusing all efforts on a specific class of molecules, possibly missing the cure, Modelis’s drug discovery pipeling considers a broad class of molecules to ensure a thorough investigation for successful drug discovery.
Modelis’ approach relies on the identification of molecules reverting sick behaviours (or phenotypes) in living organisms rather than on a tiny molecular aspect of the disease. Our approach seeks to cure the entire animal along with all associated molecular aspects of the disease.
From worms to humans, Modelis takes advantage of multiple, complementary animal models to encapsulate the complexity of the diseases in order to maximize rapid and cost-efficient drug discovery.
Modelis considers each drug discovery venture as unique and will design a specific experimental pipeline fitting your project.
Modelis’ strategy does not rely on defunct approaches. Our high-throughput pipeline allows us to test thousands of compounds and to consider unexpected candidate drugs.
Modelis’ approach is novel, taking advantage of multiple simple models in which complex diseases can be modeled in a standardised and quantifiable fashion.
Modelis’ strategy has been successfully tested in the past and brought a therapeutic solution whereas the classical approach failed.
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